One new analysis of 56 clinical trials found Avandia increased the chances of a heart attack by 28 percent to 39 percent, researchers at the Cleveland Clinic in Ohio said in an update to a 2007 study that sparked debate about the drug.
Dr. Steven Nissen, the lead author and an outspoken Avandia critic, said the results from more than 35,000 patients gave a more complete picture that reinforced his earlier concerns.
"A drug that increases the risk of heart attack by a third or more in diabetics represents a huge public health burden," Nissen, the Cleveland Clinic's head of cardiology, said in an interview. He said the drug should come off the market.
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Other Glaxo-funded studies have not shown similar heart risks and the Food and Drug Administration has backed continued sales while reviewing the medicine's risks.
- 1 vote
Ho hum...(FDA's attitude) Let's see... heart problems or diabetes... Wow!!! Both r serious issues as they both can kill ya. I'm just hopin' they don't play russian rulette w a gun loaded w 5 bullets... That would be very bad.
**Suggestion to FDA** please do thorough research on the drugs before allowing them to be put on the market... We don't need any more accidental deaths.
- 1 vote
It boggles the mind doesn't it?
"Let's just keep it on the shelf until it's been tested and found as dangerous."
As an average citizen, patients will never know about the 56 trials or an increased heart attack risk of 28-39%...?
- 2 votes
I would never accept FDA approved Pharmaceuticals for something like cancer or diabetes or heart disease. Death and major organ failure as an acceptable side effect is not acceptable. I would rather just OD on Opium and go out dreaming of something good.
- 2 votes
Death and major organ failure as an acceptable side effect is not acceptable.
I understand that there can be drugs that affect one area while helping another area. I get that. I think most people might understand that and hedge their bets. BUT when the consumers [aka patients] are not made aware of it and THEN use the rationale "Well the FDA approved it so it must be safe." that's when I get aggravated. That's what I find unacceptable.
- 2 votes
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